H5N9 Bird Flu Outbreak: Rare Strain Detected in California, Raises Public Health Concerns

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A rare strain of bird flu, H5N9, has been detected on a duck farm in California. This is the first confirmed case of HPAI H5N9 in poultry in the United States. The outbreak also found a more common H5N1 strain on the same farm. To prevent further spread, 118,954 birds were culled by December 2, 2024. Health officials are investigating, and while the public health risk remains low, those who work with birds or have recreational exposure are at higher risk. Enhanced biosecurity measures are crucial to mitigate the spread of this highly pathogenic virus.

The recent outbreak of H5N9 bird flu in California has sent shockwaves through the agricultural and public health communities. This rare strain of avian influenza, which is less common than H5N1, has been detected on a commercial duck farm in Merced County, California.

What is H5N9?

H5N9 is a subtype of the influenza A virus, which includes strains like H5N1 and H7N9. It is considered rare because it is less frequently found compared to other bird flu strains. The genetic makeup of H5N9 is unique, resulting from reassortment with other influenza subtypes such as H5N1, H7N9, and H9N21.

The Outbreak

The first confirmed case of HPAI H5N9 in poultry in the United States was reported on November 23, 2024. The outbreak began with increased mortality among ducks on the farm, leading to subsequent testing that revealed both H5N9 and H5N1 strains2. In response, the U.S. Department of Agriculture (USDA) and state animal health officials conducted comprehensive epidemiological investigations and enhanced surveillance. The affected farm was quarantined, resulting in the culling of nearly 119,000 birds by December 2, 20242.

Public Health Risk

While the current public health risk remains low, health officials are cautious about the potential for human infections. The Centers for Disease Control and Prevention (CDC) notes that direct contact with infected birds or contaminated surfaces is the primary mode of transmission to humans. Although rare, human cases have been reported in the past, particularly among those who work with birds or have recreational exposure1.

Economic Impact

1. The economic impact is further exacerbated by the reduced supply of poultry products.

Future Concerns

The emergence of H5N9 highlights the unpredictable nature of viral reassortment. Health officials are urging vigilance and enhanced surveillance to predict future developments and minimize public health risks associated with avian flu. Continuous reassessment and implementation of responsive measures are crucial to mitigating future risks to both animal and public health2.


  1. What is H5N9?
    H5N9 is a rare subtype of the influenza A virus, less common than H5N1, resulting from genetic reassortment with other subtypes like H5N1, H7N9, and H9N21.
  2. Where was the first U.S. outbreak of H5N9 detected?
    The first U.S. outbreak of H5N9 was detected on a commercial duck farm in Merced County, California2.
  3. How many birds were culled due to the outbreak?
    Nearly 119,000 birds were culled by December 2, 2024, to prevent further spread of the virus2.

  4. What is the current public health risk?
    The current public health risk remains low, but those who work with birds or have recreational exposure are at higher risk of transmission1.

  5. How does H5N9 spread to humans?
    H5N9 can spread to humans through direct contact with infected birds or contaminated surfaces, though this is rare1.

  6. What are the economic implications of the outbreak?
    The outbreak has led to higher egg prices due to the culling of millions of poultry worldwide, reducing the supply of poultry products1.

  7. What measures are being taken to mitigate the spread of H5N9?
    Enhanced biosecurity measures, comprehensive epidemiological investigations, and enhanced surveillance are being implemented to mitigate the spread of H5N92.

  8. What is the potential danger of H5N9 reassortment?
    The potential danger lies in the possibility of reassortment leading to more transmissible or virulent forms of the virus, which could increase public health risks2.

  9. How is the situation being monitored?
    The situation is being monitored closely by health officials, including the CDC and USDA, through thorough epidemiological studies and enhanced surveillance2.

  10. What is the global impact of bird flu outbreaks?
    Bird flu outbreaks have led to the culling of hundreds of millions of poultry worldwide, causing significant economic impacts and affecting global food supplies2.


The H5N9 bird flu outbreak in California highlights the need for enhanced biosecurity measures and vigilant monitoring to mitigate public health risks. While the current risk remains low, the potential for reassortment and transmission to humans underscores the importance of proactive strategies. Continuous surveillance and research are crucial to understanding the behavior of this highly pathogenic virus and preventing future outbreaks.


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